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Retinoic acid receptor ligand

Retinoic acid analog which acts as a selective RAR agonist.

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Alternative Name	Ro 13-7410, 4-[E-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetra-methyl-2-naphthalenyl)-1-propenyl]benzoic acid
Appearance	White crystalline solid.
CAS	71441-28-6
Couple Target	Retinoic acid receptor
Couple Type	Ligand
Formula	C₂₄H₂₈O₂
Identity	Determined by 1H-NMR.
MW	348.5
Purity	≥98% (HPLC)
Solubility	Soluble in DMSO or ethanol (with gentle warming).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Peroxisome Proliferator-Activated Receptor β/δ Stimulation Induces the Differentiation of Human Alveolar Epithelial Progenitor Cell: C. Ozawa, et al.; Insight. Chest. Diseas. 1, Article number 7 (2016), Application(s): Cell cultures, Immunofluorescence staining, and microscopy, Full Text
Inhibitory effects of bile acids and synthetic farnesoid X receptor agonists on rotavirus replication: Kim, Y., Chang, K. O., et al.; J. Virol. 85, 12570 (2011), Abstract
9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation: R. P. Bissonnette, et al.; Mol. Cell Biol. 15, 5576 (1995), Abstract — Full Text
Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids: M. F. Boehm, et al.; J. Med. Chem. 37, 2930 (1994), Abstract

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