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Trifluoperazine . dihydrochloride

LKT-T7033

Axxora Marketplace
  • LKT-T7033-G010   —   10 g
    $191.00
  • LKT-T7033-G025   —   25 g
    $334.00

A phenothiazine class calmodulin antagonist which is known for its inhibition of DNA synthesis and cell proliferation activities. It is shown to stimulate Egr-1 gene experession by modulating Ras/MEK/ERK and activation of the E1K-1 pathway in human fibrosarcoma HT1080 cells. Trifluoperazine also induces apoptosis in human cholangiocarcinoma cells in vitro, probably acting via the Fas system.

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Regulatory Status

RUO – Research Use Only