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Toll-like receptor 8 monoclonal antibody (44C143) (biotin conjugate)

ALX-804-376B

1 citation

  • ALX-804-376B-C100   —   100 µg
    Biotin
    $530.00

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kDa.

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Regulatory Status

RUO – Research Use Only