TNP-β-L-GTP

Fluorescent analogue of β-L-GTP, the mirror image version of naturally occurring β-D-GTP, where the guanine nucleobase is connected to β-L-ribose. TNP fluorophore with λexc 408 nm and λem 552 nm. It is sensitive to indicators of local environment such as polarity and viscosity, and frequently exhibits a spectral shift and fluorescence enhancement upon binding to a protein. Potential inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC).