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The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.
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Immunohistochemistry analysis of human spleen cells using TLR2 antibody at 2µg/ml.
Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1µg/ml in the presence (A) and absence (B) of its blocking peptide.
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RUO – Research Use Only |
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