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PI3 kinase p110β inhibitor

Potent, selective and cell permeable inhibitor of phosphoinositide 3-kinase (PI(3)K) p110β.

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Alternative Name	7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido-[1,2-a]pyrimidin-4-one
Appearance	Pale yellow solid.
CAS	663619-89-4
Couple Target	PI3 kinase
Couple Type	Inhibitor
Formula	C₂₁H₂₄N₄O₂
MW	364.4
Purity	≥98% (NMR)
Solubility	Soluble in DMSO, 100% ethanol or dimethyl formamide; sparingly soluble in aqueous buffers.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils: A.M. Condliffe, et al.; Blood 106, 1432 (2005), Abstract — Full Text
PI 3-kinase p110beta: a new target for antithrombotic therapy: S.P. Jackson, et al.; Nat. Med. 11, 507 (2005), Abstract — Full Text

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