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Tetanus toxoid

ALX-630-108

8 citations

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Inactivation with formaldehyde leads to non-toxic form of tetanus toxin.

Produced from tetanus toxin by inactivation with formaldehyde. The resulting toxoid is essentially non-toxic.

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Product Details

Alternative Name	Formaldehyde inactivated tetanus toxin
Concentration	0.5μg/μl after reconstitution.
Formulation	Lyophilized.
MW	~150kDa
Quality Control	Immunoprecipitation; concentration determination by UV absorbance.
Reconstitution	Reconstitute with 200μl distilled water to get a 0.5μg/μl solution in 100mM histidine, 100mM sodium chloride and 5% trehalose, pH 7.0.
UniProt ID	P04958

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stock solutions are stable for up to 6 months when stored at -20°C.
Handling	Sealed under vacuum. Do not exceed one freeze/thaw cycle. Do not vortex. After reconstitution, prepare aliquots and store at -20°C.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Lateral Flow-Based Skin Patch for Rapid Detection of Protein Biomarkers in Human Dermal Interstitial Fluid: E.C. Wilkirson, et al.; ACS Sens. , (2024), Abstract
Development of a bead-based multiplex immunoassay for simultaneous quantitative detection of IgG serum antibodies against seven vaccine-preventable diseases: E.N. Bykonia, et al.; J. Immunol. Methods 512, 113408 (2023), Abstract
Immunocompromised Patients with Therapy-Refractory Chronic Skin Diseases Show Reactivation of Latent Epstein-Barr Virus and Cytomegalovirus Infection: P. Speth, et al.; J. Invest. Dermatol. 142, 549 (2022), Abstract
Structural basis of tetanus toxin neutralization by native human monoclonal antibodies: Wang, Y., Wu, C., et al.; Cell Rep. 35, 109070 (2021), Abstract
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor: K.G. MacDonald, et al.; J. Clin. Invest. 126, 1413 (2016), Abstract — Full Text
Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy: E. Esser, et al.; J. Control Release 236, 47 (2016), Application(s): ELISA for humoral immune responses, Abstract
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy: R. Bacchetta, et al.; Haematologica 95, 2134 (2010), Abstract — Full Text
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity: T. Rubic, et al.; Nat. Immunol. 9, 1261 (2008), Abstract

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Last modified: May 29, 2024

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Tetanus toxoid

ALX-630-108

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