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Temozolomide

ALX-420-044

17 citations

  • ALX-420-044-M025   —   25 mg
    $117.00
  • ALX-420-044-M100   —   100 mg
    $403.00
  • ALX-420-044-M500   —   500 mg
    $1,334.00

Antitumor and antiangiogenic compound. DNA alkylating agent. Induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA. Inactivates DNA repair protein O(6)-alkylguanine DNA alkyltransferase (AGT) in base excision repair (BER) pathway. Chemotherapeutic agent. Modifies drug resistance.

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Regulatory Status

RUO – Research Use Only