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Teleocidin A1 is a selective protein kinase C activator representing a new class of non-phorbol ester tumor promotors. Teleocidin A1 mimics the effect of diacylglycerol (DAG), activating PKC, but unlike DAG causes persistent activation. It enhances actin redistribution, vacuole formation and c-fos expression in PLC/PRF/5 hepatoma cells. Occurs in toxic cyanobacterial blooms.
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