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TACI (transmembrane activator and CAML interactor), also known as TNF receptor superfamily member 13B, is a lymphocyte-specific member of the TNF-R family. TACI and its ligands (BAFF, APRIL) regulate humoral immune responses, activate NF-κB and c-jun N-terminal kinase, and play a role in B cell associated autoimmune diseases. Mutations in TACI are associated with a subset of common variable immunodeficiency (CVID).
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Immunocytochemistry analysis of TACI in K562 cells with TACI antibody at 2µg/ml.
Western blot analysis of TACI in K562 (A) and U937 (B) cell lysates with TACI antibody at 5µg/ml.
| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Application | ELISA, IHC, WB |
|---|---|
| Host | Goat |
| Species Reactivity | Rabbit |