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Storage and dilution buffer for use with the following product:
SUPERKILLERTRAIL® , Soluble (human) (recombinant) (Prod. No. ALX-201-115)
Useful for prediluting the above mentioned product before preparing aliquots or performing experiments. Predilution with SUPERKILLERTRAIL® Storage and Dilution Buffer allows for easier handling of small working concentrations (sometimes only 0.1µl of the SUPERKILLERTRAIL® stock solution is necessary because of their high activity). Predilution with SUPERKILLERTRAIL® Storage and Dilution Buffer instead of medium or PBS prevents loss of biological activity. Can also be used as negative control.
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| Regulatory Status |
RUO – Research Use Only |
|---|
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SUPERKILLERTRAIL® Protein (soluble) (human), (recombinant)
ALX-201-115
Enhanced ligand with improved stability providing significantly enhanced immune activation.
| Alternative Name | TNFSF 10, Apo-2L, CD253 |
|---|---|
| Purity | ≥98% (SDS-PAGE). MS analysis, <1% impurity (mainly Hsp70 protein from E. coli) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. |