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SUMO (small ubiquitin-related modifier) is a member of a family of ubiquitin-like proteins involved in the regulation of the cellular functions of a wide variety of proteins. Four members of the SUMO family have been described in vertebrates, SUMO-1 and the close homologues SUMO-2 and SUMO-3, with some 50% homology between SUMO-1 and SUMO-2/3. Although a fourth SUMO (SUMO-4) has been reported, there remains considerable debate as to whether this is a real and expressed gene product.
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Figure 1: Hela cells were fixed with paraformaldehyde and stained with SUMO-2 antibody (BML-PW0510A) at 1:50 dilution.
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RUO – Research Use Only |
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