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Suberoyl bis-hydroxamic acid

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HDAC inhibitor

Induces cellular differentiation. Inhibits histone deacetylation.

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Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells: Z. Barjaktarovic, et al.; J. Radiat. Res. 56, 623 (2015), Application(s): Cell Culture, Abstract — Full Text
Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma: Yee, N. S., Zhou, W., et al.; Cancer Lett. 318, 99 (2012), Abstract
Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells: K. Huber, et al.; J. Biol. Chem. 286, 22211 (2011), Abstract — Full Text
Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock: Li, Y., Liu, B., et al.; Surgery 150, 442 (2011), Abstract
Cytodifferentiating agents affect the replication of herpes simplex virus type 1 in the absence of functional VP16: C.M. Preston & M. McFarlane; Virology 249, 418 (1998), Abstract

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