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STT Negative Control for Gelatinase

BML-PI137

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MMP inhibitor

STTHWGFTLS is ten times less potent than, thus a negative control for CTTHWGFTLC (Prod. No. BML-PI136), which is a specific inhibitor of the gelatinases MMP-2 and MMP-9. Can be used in in vitro studies, zymography and in situ zymography, in tissue culture, and in vivo.

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Product Details

Appearance	White to off-white solid.
Formulation	Lyophilized.
MW	1136.2
Purity	≥95% (HPLC)
Sequence	H-Ser-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Ser-OH
Solubility	Soluble in water (10mg/ml) or DMSO.
Source	Synthetic.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Handling	Protect from moisture. After reconstitution, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro: O.P. Medina, et al.; Cancer Res. 61, 3978 (2001), Abstract
Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction: C. Fernandez-Patron, et al.; Circ. Res. 87, 670 (2000), Abstract
Tumor targeting with a selective gelatinase inhibitor: E. Koivunen, et al.; Nat. Biotechnol. 17, 768 (1999), Abstract

Related Products

CTT

BML-PI136

MMP inhibitor

1 citation

Purity	≥95% (HPLC)
Source	Synthetic.

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STT Negative Control for Gelatinase

BML-PI137

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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