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Sterigmatocystin

ALX-630-116

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Mycotoxin

Mycotoxin produced by strains of the common molds. Inhibitor of DNA synthesis. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.

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Product Details

Alternative Name	3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3’,2’:4,5]furo[2,3-c]xanthen-7-one
Appearance	Pale yellow solid.
CAS	10048-13-2
Formula	C₁₈H₁₂O₆
MW	324.3
Purity	≥98% (TLC, HPLC)
RTECS	LV1750000
Solubility	Soluble in DMSO (10mg/ml), chloroform (71mg/ml), pyridine (18mg/ml) or acetone (5mg/ml).
Source	Isolated from Aspergillus versicolor.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ): D.S. Yao, et al.; Bioelectrochemistry 68, 126 (2006), Abstract
An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin: K.C. Ehrlich, et al.; Appl. Environ. Microbiol. 71, 8963 (2005), Abstract — Full Text
Aspergillus mycotoxins and their effect on the host: K. Kamei & A. Watanabe; Med. Mycol. 43, S95 (2005), Abstract
Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bünger, et al.; Toxicology 202, 199 (2004), Abstract
Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res. 137, 111 (1984), Abstract
Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn. 23, 647 (1973), Abstract
Effect of sterigmatocystin on rat liver nuclear RNA: W. Nel & H.E. Pretorius; Biochem. Pharmacol. 19, 957 (1970), Abstract

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Sterigmatocystin

ALX-630-116

Product Details

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