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Spantide III

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Substance P antagonist

A superior substance P antagonist with high potency and negligible neurotoxicity. More effective than spantide II.

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Appearance	White to off-white powder.
Formulation	Lyophilized.
MW	1630.8
Purity	≥98% (HPLC)
Sequence	N-ε-Nicotinoyl-D-Lys-Pro-3-Pyridyl-Ala-Pro-D-Cl₂Phe-Asn-D-Trp-Phe-D-3-Pyridyl-Ala-Leu-Nle-NH₂
Solubility	Soluble in Water.
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats: S. Hishida, et al.; Nagoya J. Med. Sci. 78, 215 (2016), Application(s): Injected into submandibular rat glands, Abstract — Full Text
Spantide III, a superior tachykinin antagonist with high potency and negligible neurotoxicity: K. Folkers, et al.; Amino Acids 5, 233 (1993), Abstract

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