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Sp100 (human) polyclonal antibody

BML-PW0325

  • BML-PW0325-0025   —   25 µl
    $161.00
  • BML-PW0325-0100   —   100 µl
    $560.00

Sp100 is an interferon-inducible protein and a major constituent of distinct nuclear domains, known as nuclear dots (NDs) or PML bodies. NDs play a role in autoimmunity, virus infections, and in the etiology of acute promyelocytic leukaemia. SUMO modification of Sp100 has been shown to promote interaction of Sp100 with non-histone chromosomal proteins, suggesting a regulatory role in chromatin organization and in functional interplay between these nuclear bodies and chromatin.

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Regulatory Status

RUO – Research Use Only