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Membrane-permeant inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) but activator of cyclic GMP-dependent protein kinase I α and I β (cGMP agonist). Suitable for distinction between kinase and ion channel mediated effects. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterase, no metabolic side effects. More lipophilic and permeant as compared to Sp-8-pCPT-cGMPS (Prod. No. BLG-C014).
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RUO – Research Use Only |
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