Sp-8-Br-PET-cGMPS

Membrane-permeant inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) but activator of cyclic GMP-dependent protein kinase I α and I β (cGMP agonist). Suitable for distinction between kinase and ion channel mediated effects. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterase, no metabolic side effects. More lipophilic and permeant as compared to Sp-8-pCPT-cGMPS (Prod. No. BLG-C014).

BLG-P008-25 (5 x 5 µmol pack size) is not sold in the U.S. or Canada. Please contact us for available options.