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Sp-8-Br-cGMPS

BML-CN217

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cGMP agonist

Cell-permeable, phosphodiesterase-resistant cGMP agonist. This analog activates PKA and PKG with similar potency. Much more lipophilic and membrane permeant as compared to cyclic GMP (Prod. No. ALX-480-059) or Sp-cGMPS (Prod. No. ALX-480-073)

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Product Details

Appearance	Lyophilized solid.
CAS	153660-03-8
Couple Target	PKA, PKG
Couple Type	Inhibitor
Formula	C₁₀H₁₀BrN₅O₆PS . Na
MW	462.2
Purity	≥98% (HPLC)
Solubility	Soluble in water (25mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Evidence for two intracellular calcium pools in Dictyostelium: the cAMP-induced calcium influx is directed into a NBD-Cl- and 2,5-di-(tert-butyl)1,4-hydroquinone-sensitive pool: H. Flaadt et al.; J. Cell. Sci. 105 ( Pt 4), 1131 (1993), Abstract

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Sp-8-Br-cGMPS

BML-CN217

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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