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SHPRH (human), (recombinant)

ENZ-PRT361

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SHPRH possesses both helicase and E3 ubiquitin ligase activities. It belongs to a family of SNF2-related nucleosome remodeling enzymes (DNA-dependent ATPases). These ATP-dependent motor proteins are major factors of chromatin structure and transcriptional control in vivo. SNF2-related factors have been implicated in a variety of cancers in humans.

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Product Details

Alternative Name	E3 ubiquitin-protein ligase SHPRH, RAD5, KIAA2023
Formulation	Liquid. In 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl₂, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin.
MW	~195 kDa
Purity Detail	Purified by immunoaffinity chromatography.
Source	Produced in insect (Sf9) cells. Human SHPRH (aa 1-1682) fused to 6xHis and FLAG-tag at the N-terminus.
UniProt ID	Q149N8-1

Handling & Storage

Handling	Thaw and freeze quickly, in room-temperature water bath and liquid nitrogen, respectively; keep on ice when not in storage; split in small aliquots upon first thawing; avoid excessive freeze-thaw cycles.
Long Term Storage	-80°C
Shipping	Dry Ice

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SHPRH (human), (recombinant)

ENZ-PRT361

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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