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Serotonin . hydrochloride

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Neurotransmitter

Neurotransmitter. Endogenous 5-HT agonist produced by serotonergic neurons in the CNS and enterochromaffin cells in the gastrointestinal tract.

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Alternative Name	5-Hydroxytryptamine . HCl
Appearance	White to gray crystalline powder.
CAS	153-98-0
Couple Target	Serotonin receptor
Couple Type	Activator, Ligand
Formula	C₁₀H₁₂N₂O . HCl
MI	14: 8462
MW	176.2 . 36.5
Purity	≥98% (HPLC)
Solubility	Soluble in water, methanol or 100% ethanol.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light. Hygroscopic.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Psychedelic-inspired drug discovery using an engineered biosensor: Dong, C., Ly, C., et al.; Cell 184, 2779 (2021), Abstract
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning: Unger, E. K., Keller, J. P., et al.; Cell 183, 1986 (2020), Abstract
Serotonin as a neurotransmitter in cerebral arteries: S.G. Griffith, et al.; Brain Res. 247, 388 (1982), Abstract

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