Easy-to-use, well-validated serotonin ELISA kit for hormone research.
- Highly sensitive measurement of serotonin, detecting as little as 0.293 ng/ml
- No acylation required for standards and samples
- Thoroughly validated in multiple complex sample matrices
- High throughput format with results in just 3 hours for up to 39 samples in duplicate
- Fully quantitative results that surpass semi-quantitiave Western blot analysis
The Serotonin EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours.
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine found in the central nervous system, gastrointestinal tract, and blood with broad physiological functions in neurotransmission, gastric motility, hemostasis, and cardiovascular integrity. Seven subclasses (5-HT 1-7) of serotonin receptors have been identified, a majority of which are members of the seven transmembrane domain-containing GPCR family, and are the target of several anti-depressant drugs. The 5-HT1 subclass consists of five highly homologous receptors that couple via G(i/o) alpha subunits to inhibit adenylyl cyclase activity. 5-HT1A expression in mammals is strongest in CNS limbic pathways that control emotion, including tissue of the hippocampus, dorsal raphé, and septum. Serotonin is a key biomarker used for the monitoring of overall welfare and/or the assessment of behavioral disorders in a variety of species.
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Product Details
| Alternative Name |
5-HT, 5-hydroxytryptamine |
|---|---|
| Application |
Colorimetric detection, ELISA |
| Application Notes |
For the quantitative determination of Serotonin in platelets, plasma, serum, and urine from any species. Cited sample type includes culture supernatant. |
| Assay Time |
3 hours |
| Compatibility |
This product is compatible with the Absorbance 96 Plate Reader. |
| Contents |
GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
| Crossreactivity |
N-acetyl serotonin (17%), 5-hydroxy-L-tryptophan (0.4%), Tryptamine (0.1%), 5-hydroxyindoleacetic acid (0.03%), Melatonin (0.01%), Tyramine (<0.004%), Tryptophan (<0.004%) |
| Sensitivity |
0.293 ng/ml (range 0.49 – 500 ng/ml) |
| Species Reactivity |
Species independent |
| Technical Info / Product Notes |
Application Note: Cited samples: |
| Wavelength |
405 nm |
Handling & Storage
| Use/Stability |
Store all components at -20°C |
|---|---|
| Shipping |
Blue Ice |
| Regulatory Status |
RUO – Research Use Only |
|---|
- Serotonin 2A Receptor Attenuates Psoriatic Inflammation by Suppressing IL-23 Secretion in Monocyte-derived Langerhans Cells: Lee, Y., Tan, Y. F., et al.; Research Square , (2025), Sample Type: serum (Human) and cell lysate (Mouse platelets)
- Impact of initial postweaning feed intake on weanling piglet metabolism, gut health, and immunity: Fabà, L., Martín-Orúe, S. M., et al.; J. Anim. Sci. 103, skaf099 (2025), Sample Type: Pig plasma, Abstract
- Tryptophan promotes sperm hyperactivation in hamsters via 5-hydroxytryptamine biosynthesis within sperm: Suzuki, I., Fujinoki, M., et al.; J. Reprod. Dev. , (2025), Sample Type: Rodent (Syrian hamsters [Mesocricetus auratus]) other (sperm), Abstract
- Serotonin 2A receptor attenuates psoriatic inflammation by suppressing IL-23 secretion in monocyte-derived Langerhans cells.: Tan, Y. F., Yeh, C. Y., et al.; Nat. Commun. 16, 8544 (2025), Sample Type: Serum (Human) and cell lysate (Mouse platelets), Abstract
- Weight loss reverses obesity-associated impairments in acute gastrointestinal stretch-induced suppression of food intake and glucose homeostasis.: Bethea, M., Cook, T., et al.; Mol. Metab. 102, 102260 (2025), Abstract
- GABALAGEN Facilitates Pentobarbital-Induced Sleep by Modulating the Serotonergic System in Rats: M. Ye, et al.; Curr. Issues Mol. Biol. 46, 11176 (2024), Sample Type: Rat serum, Abstract
- Downregulation of Serotonergic System Components in an Experimentally Induced Cryptorchidism in Rabbits: Jiménez-Trejo, F., Arriaga-Canon, C., et al.; Int. J. Mol. Sci. 25, (2024), Sample Type: Rodent (Rabbit [Oryctolagus cuniculus]) tissue lysate (testis), Abstract
- Effects of Barefoot Walking in Urban Forests on CRP, IFNγ, and Serotonin Levels: Kim, J. S., Lee, M. M., et al.; Healthcare (Basel) 12, (2024), Sample Type: Human saliva, Abstract
- Effects of Somatosensory Games on Heart Rate Variability and Sleep-Related Biomarkers in Menopausal Women With Poor Sleep Quality: Lin, Y. Y., Liao, Y. H., et al.; Innov. Aging 8, igae072 (2024), Sample Type: Human serum, Abstract
- Identification, quantification, and antidepressant-like evaluation of anthocyanin-rich extracts from different dietary berries: Wang, J., Cheng, J., et al.; Food. Sci. Nutr. 12, 6315 (2024), Sample Type: Mouse serum, Abstract
- Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia: Ferraz-Bannitz, R., Ozturk, B., et al.; J. Clin. Invest. 134, (2024), Sample Type: Human and Mouse plasma, Abstract
- SIRT6 regulates Tryptophan catabolism preventing metabolite imbalance and neurodegeneration: Toiber, D., Kopatch, S. K., et al.; Research Square , (2024), Sample Type: Mouse serum
- SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology: K.E. Zengeler, et al.; Brain Behav. Immun. Health 108, 80 (2023), Sample Type: Mouse serum and tissue lysate (maternal-fetal interface [decidua, placenta, uterine muscle]), Abstract
- Association between Low Vitamin D Status, Serotonin, and Clinico-Biobehavioral Parameters in Alzheimer’s Disease: A. L. Richter, et al.; Dement. Geriatr. Cogn. Disord. 52, 318 (2023), Sample Type: Human serum, Abstract
- A New Perspective on the Pathogenesis of Infantile Colic: Is Infantile Colic a Biorhythm Disorder?: Ucuncu Egeli, T., Tufekci, K. U., et al.; J. Pediatr. Gastroenterol. Nutr. 77, 171 (2023), Sample Type: Human urine, Abstract
- Chronic HDM exposure shows time-of-day and sex-based differences in inflammatory response associated with lung circadian clock disruption: Srinivasan, A., Giri, A., et al.; iScience 26, 107580 (2023), Sample Type: Mouse serum, Abstract
- Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin: Fernando, S. J. A., Wang, Q., et al.; Biosci. Rep. 43, (2023), Sample Type: Human Culture supernatant ( Colo320 lagre intestine adenocarcinoma cell line), Abstract
- Skeletal effects following developmental flame-retardant exposure are specific to sex and chemical class in the adult Wistar rat: Schkoda, S., Horman, B., et al.; Front. Toxicol. 5, 1216388 (2023), Sample Type: Rat serum, Abstract
- Lipids regulate peripheral serotonin release via gut CD1d.: Luo, J., Chen, Z., et al.; Immunity 56, 1533 (2023), Abstract
- Phytochemical screening and effect of Viscum album L. on monoamine oxidase A and B activity and serotonin, dopamine and serotonin receptor 5-HTR1A levels in Galleria mellonealla (Lepidoptera): A. Szurpnicka, et al.; J. Ethnopharmacol. 298, 115604 (2022), Sample Type: Insect ( Wax moth [Galleria mellonella]) other (larval hemolymph), Abstract
- Improvement of several stress response and sleep quality hormones in men and women after sleeping in a bed that protects against electromagnetic fields: E.D.D. Cerro, et al.; Environ. Health 21, 72 (2022), Sample Type: Human plasma, Abstract
- Telotristat ethyl reverses myxomatous changes in mice mitral valves: X. Wang, et al.; Front. Cardiovasc. Med. 9, 945672 (2022), Sample Type: Mouse other (whole blood), Abstract
- Enhanced presence of serotonin in nasal cavity after autologous stimulation: F. Salvinelli, et al.; Eur. Rev. Med. Pharmacol. Sci. 256, 2970 (2022), Sample Type: Human other (nasal scraping), Abstract
- Modulation of Intestinal Corticotropin-Releasing Hormone Signaling by the Herbal Preparation STW 5-II: Possible Mechanisms for Irritable Bowel Syndrome Management: M. Elbadawi, et al.; Pharmaceuticals (Basel) 15, 1121 (2022), Sample Type: Mouse Culture supernatant (intestinal organoids), Abstract
- Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome: Z.A. Barandouzi, et al.; Sci. Rep. 12, 1648 (2022), Sample Type: Human plasma, Abstract
- Gut bacterial aromatic amine production: aromatic amino acid decarboxylase and its effects on peripheral serotonin production: Y. Sugiyama, et al.; Gut Microbes 14, 2128605 (2022), Sample Type: Mouse tissue lysate (colon), Abstract
- Association of Serum Glucose, Serotonin, Aspartate Aminotransferase, and Calcium Levels with Meat Quality and Palatability Characteristics of Broiler Pectoralis Major Muscle: Lee, B., Choi, Y. M., et al.; Animals (Basel) 12, (2022), Sample Type: Bird (Chicken) plasma, Abstract
- Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota-Gut-Brain Axis Modulation in a Valproic Acid Mouse Model: Serra, D., Henriques, J. F., et al.; Int. J. Mol. Sci. 23, (2022), Sample Type: Mouse tissue lysate (prefrontal cortex, ileum, and colon), Abstract
- Effects of serum aspartate aminotransferase activity on levels of serum Ca2+, Ca2+ channel genes, apoptotic factors, and meat quality characteristics of chicken pectoralis major muscle: Lee, B., Kim, J. Y., et al.; Poult. Sci. 101, 102214 (2022), Sample Type: Bird (Chicken) plasma, Abstract
- Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A: Owaki, T., Kamimura, K., et al.; Dis. Model. Mech. 15, (2022), Sample Type: serum (Human and Mouse), Abstract
- Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors: Edvinsson, J. C. A., Maddahi, A., et al.; J. Headache Pain 23, 26 (2022), Sample Type: Rat tissue lysate (trigeminal ganglion), Abstract
- Maternal diet disrupts the placenta-brain axis in a sex-specific manner: Ceasrine, A. M., Devlin, B. A., et al.; Nat. Metab. 4, 1732 (2022), Sample Type: Mouse plasma and tissue lysate (placenta and brain), Abstract
- Mechanistic Studies of Gypenosides in Microglial State Transition and its Implications in Depression-Like Behaviors: Role of TLR4/MyD88/NF-κB Signaling: Cao, L. H., Zhao, Y. Y., et al.; Front. Pharmacol. 13, 838261 (2022), Sample Type: Mouse tissue lysate (brain), Abstract
- Mucosal Serotonin Reuptake Transporter Expression in Irritable Bowel Syndrome Is Modulated by Gut Microbiota Via Mast Cell-Prostaglandin E2: Gao, J., Xiong, T., et al.; Gastroenterology 162, 1962 (2022), Sample Type: Mouse plasma, Abstract
- Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats: Ghaheri, S., Niapour, A., et al.; Int. J. Dev. Neurosci. 82, 222 (2022), Sample Type: Rat tissue lysate (brain hippocampus and prefrontal cortex), Abstract
- Serotonin-1A receptor, a psychiatric disease risk factor, influences offspring immunity via sex-dependent genetic nurture: Chen, R. J., Nabila, A., et al.; iScience 25, 105595 (2022), Sample Type: Mouse plasma, Abstract
- Analysis of cytokine levels, T regulatory cells and serotonin content in patients with depression: J. Obermanns, et al.; Eur. J. Neurosci. 53, 3476 (2021), Sample Type: Human serum, Abstract
- Serotonin involvement in okadaic acid-induced diarrhoea in vivo: M.C. Louzao, et al.; Arch. Toxicol. 95, 2797 (2021), Sample Type: Mouse tissue lysate (Intestine), Abstract
- Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4: A. Salama, et al.; Immunopharmacol. Immunotoxicol. 43, 309 (2021), Sample Type: Rat tissue lysate (Brain), Abstract
- Airway basal stem cells generate distinct subpopulations of PNECs: H. Mou, et al.; Cell Rep. 35, 109011 (2021), Sample Type: Human serum, Abstract
- Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes: N. Nakatsuka, et al.; Mol. Psychiatry 26, 2753 (2021), Sample Type: Human culture supernatant (iPSC-derived serotonergic neurons), Abstract
- Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice: Aliluev, A., Tritschler, S., et al.; Nat. Metab. 3, 1202 (2021), Sample Type: Mouse plasma, Abstract
- Epididymal Fat-Derived Sympathoexcitatory Signals Exacerbate Neurogenic Hypertension in Obese Male Mice Exposed to Early Life Stress: Dalmasso, C., Leachman, J. R., et al.; Hypertension 78, 1434 (2021), Sample Type: Mouse tissue lysate (epididymal white adipose tissue), Abstract
- Evaluation of Euthanasia Methods on Behavioral and Physiological Responses of Newly Hatched Male Layer Chicks: Wang, X., Zhao, D., et al.; Animals (Basel) 11, (2021), Sample Type: Bird (Chicken) serum, Abstract
- Minimally invasive biomarkers to detect maternal physiological status in sow saliva and milk: Hall, S. A., Farish, M., et al.; Animal 15, 100369 (2021), Abstract
- Neurohormonal Profiles of Assistance Dogs Compared to Pet Dogs: What Is the Impact of Different Lifestyles?: Mengoli, M., Oliva, J. L., et al.; Animals (Basel) 11, (2021), Sample Type: Canine (Dog) serum, Abstract
- Tryptophan metabolism is dysregulated in individuals with Fanconi anemia: Bartlett, A. L., Romick-Rosendale, L., et al.; Blood Adv. 5, 250 (2021), Sample Type: Human plasma, Abstract
- Water intake releases serotonin from enterochromaffin cells in rat jejunal villi: Kajihara, R., Amari, K., et al.; Pflugers Arch. 473, 921 (2021), Sample Type: Rat plasma and other (mesenteric lymph), Abstract
- Assessing donor-to-donor variability in human intestinal organoid cultures.: Mohammadi, S., Morell-Perez, C., et al.; Stem Cell Reports 16, 2364 (2021), Abstract
- Platelet inhibition by ticagrelor is protective against diabetic nephropathy in mice: M. Uil, et al.; FASEB J. 34, 13750 (2020), Sample Type: Mouse plasma, Abstract — Full Text
- Perinatal androgens organize sex differences in mast cells and attenuate anaphylaxis severity into adulthood: E. Mackey, et al.; PNAS 117, 23751 (2020), Sample Type: Mouse Culture supernatant (Dendritic cells, BMMCs), Abstract
- Coagulation Profiles of Pulmonary Arterial Hypertension Patients, Assessed by Non-Conventional Hemostatic Tests and Markers of Platelet Activation and Endothelial Dysfunction: E. Vrigkou, et al.; Diagnostics (Basel) 10, 758 (2020), Sample Type: Human plasma, Abstract
- Effects on tactile transmission by serotonin transporter inhibitors at Merkel discs of mouse whisker hair follicles: W. Chang & J.G. Gu; Mol. Pain 16, 1744806920938230 (2020), Sample Type: Mouse other (Hair follicle), Abstract — Full Text
- Unexpected effects of long-term treatment with acetylsalicylic acid on late phase of pulmonary metastasis in murine model of orthotopic breast cancer: M. Smeda, et al.; PLoS One 15, e0230520 (2020), Sample Type: Mouse plasma and tissue lysate (Lung), Abstract — Full Text
- Altered levels of salivary and plasma pain related markers in temporomandibular disorders: Jasim, H., Ghafouri, B., et al.; J. Headache Pain 21, 105 (2020), Sample Type: Human plasma and saliva, Abstract
- Apoptosis signal-regulating kinase 1 regulates immune-mediated thrombocytopenia, thrombosis, and systemic shock: Patel, P., Shaik, N. F., et al.; J. Thromb. Haemost. 18, 3013 (2020), Sample Type: Mouse Culture supernatant (platelets), Abstract
- Effect of colostrum feeding strategies on the expression of neuroendocrine genes and active gut mucosa-attached bacterial populations in neonatal calves: Hromádková, J., Suzuki, Y., et al.; J. Dairy Sci. 103, 8629 (2020), Sample Type: Cow plasma, Abstract
- A prospective study of the pathophysiology of carcinoid crisis: M.E. Condron, et al.; Surgery 165, 158 (2019), Sample Type: Human serum, Abstract
- Prolongation of bronchopulmonary C-fiber–mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT3 receptors: L. Zhao, et al.; FASEB J. 33, 10731 (2019), Sample Type: Rat other (BALF), Abstract
- Nppb neurons are sensors of mast cell-induced itch: H.J. Solinski, et al.; Cell Rep. 26, 3561 (2019), Sample Type: Mouse Culture supernatant (Mast cells), Abstract — Full Text
- Effects of anisomycin infusions into the dorsal striatum on memory consolidation of intense training and neurotransmitter activity: D.A. Gonzalez-Franco, et al.; Brain Res. Bull. 150, 250 (2019), Sample Type: Rat tissue lysate (Dorsal striatum), Abstract
- Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis: T.A.M. Claushuis, et al.; J. Innate Immun. 11, 168 (2019), Sample Type: Mouse plasma, Abstract — Full Text
- Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway: X. Zhang, et al.; Invest. Ophthalmol. Vis. Sci. 60, 419 (2019), Sample Type: Human other (Tear), Abstract — Full Text
- Potential Antimigraine Effects of Warfarin: An Exploration of Biological Mechanism with Survey of Patients: B. Nilsson, et al.; TH Open 3, e180 (2019), Sample Type: Human Culture supernatant (Platelets), Abstract — Full Text
- Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch: Meixiong, J., Anderson, M., et al.; Immunity 50, 1163 (2019), Sample Type: Mouse cell lysate and culture supernatant (primary peritoneal mast cells ), Abstract
- Platelet abnormalities in Huntington’s disease: Denis, H. L., Lamontagne-Proulx, J., et al.; J. Neurol. Neurosurg. Psychiatry 90, 272 (2019), Sample Type: Human Culture supernatant (platelets), Abstract
- Probiotic Supplementation During Human Pregnancy Affects the Gut Microbiota and Immune Status: Chen, Y., Li, Z., et al.; Front. Cell. Infect. Microbiol. 9, 254 (2019), Sample Type: Human serum, Abstract
- Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice: S.H. Lee, et al.; J. Allergy Clin. Immunol. 142, 1349 (2018), Sample Type: Mouse tissue lysate (Skin), Abstract
- Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus: H. Jiao, et al.; Neuropsychiatr. Dis. Treat. 15, 21 (2018), Sample Type: Rat tissue lysate (Hippocampus), Abstract — Full Text
- Evaluation of alternative euthanasia methods of neonatal chickens: S. Gurung, et al.; Animals (Basel) 8, 37 (2018), Sample Type: Bird (Chicken) serum, Abstract — Full Text
- Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway: S. Niture, et al.; Cell Commun. Signal. 16, 78 (2018), Sample Type: Human cell lysate (HepG2 and Sk-Hep1 cells), Abstract — Full Text
- Hashimoto’s thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice: Y. J. Cai, et al.; J. Neuroinflammation 15, 299 (2018), Sample Type: Mouse serum and tissue lysate (Frontal cortex), Abstract — Full Text
- Use of calcitriol to maintain postpartum blood calcium and improve immune function in dairy cows: A. Vieira-Neto, et al.; J. Dairy Sci. 100, 5805 (2018), Sample Type: Cow plasma, Abstract
- Carbon Dioxide and Nitrogen Infused Compressed Air Foam for Depopulation of Caged Laying Hens: S. Gurung, et al.; Animals (Basel) 8, E6 (2018), Sample Type: Bird (Chicken) serum, Abstract — Full Text
- Fecal Microbiota Transplantation Can Alleviate Gastrointestinal Transit in Rats with High-Fat Diet-Induced Obesity via Regulation of Serotonin Biosynthesis: W. Sun, et al.; Biomed. Res. Int. 2018, 8308671 (2018), Sample Type: Rat serum and tissue lysate (Small intestine, colon), Abstract — Full Text
- Long-Term Diet Supplementation with Lactobacillus paracasei K71 Prevents Age-Related Cognitive Decline in Senescence-Accelerated Mouse Prone 8: H.M. Corpuz, et al.; Nutrients 10, E762 (2018), Sample Type: Mouse serum and tissue lysate (Brain), Abstract — Full Text
- Linalool ameliorates memory loss and behavioral impairment induced by REM-sleep deprivation through the serotonergic pathway: B.K. Lee, et al.; Biomol. Ther. 26, 368 (2018), Sample Type: Mouse tissue lysate (Hippocampus), Abstract — Full Text
- Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis: T.A.M. Claushuis, et al.; Platelets 12, 1 (2018), Sample Type: Human plasma, Abstract — Full Text
- Providing straw to allow exploratory behaviour in a pig experimental system does not modify putative indicators of positive welfare: peripheral oxytocin and serotonin: M. Marcet Rius, et al.; Animal 12, 2138 (2018), Sample Type: Pig (Mini-pigs) plasma, Abstract
- Dose-response relationship of tryptophan with large neutral amino acids, and its impact on physiological responses in the chick model: A.U. Bello, et al.; Gen. Comp. Endocrinol. 260, 146 (2018), Sample Type: Bird serum, Abstract
- Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks.: De Vadder, F., Grasset, E., et al.; PNAS 115, 6458 (2018), Abstract
- Association between salivary serotonin and the social sharing of happiness: M. Matsunaga, et al.; PLoS One 12, e0180391 (2017), Sample Type: Human Saliva, Abstract — Full Text
- Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R: B. Pfanzagl, et al.; Sci. Rep. 7, 1313 (2017), Sample Type: Human cell lysate (P-STS cells), Abstract — Full Text
- Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice: Zhu, X., Shen, W., et al.; Signal Transduct. Target Ther. 2, 17017 (2017), Sample Type: Mouse tissue lysate (colon), Abstract
- Postpartum Lactation-Mediated Behavioral Outcomes and Drug Responses in a Spontaneous Mouse Model of Obsessive-Compulsive Disorder: Mitra, S., Mucha, M., et al.; ACS Chem. Neurosci. 8, 2683 (2017), Sample Type: Mouse serum, Abstract
- Suicide, Impulsivity and its Relationship to Platelet Serotonin Levels: A. Kumar, et al.; IJCMR 3, 3077 (2016), Sample Type: Human other (Platelets), Full Text
- M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus: C.S. Lam, et al.; PLoS One 11, e0166966 (2016), Sample Type: Rat tissue lysate (Hippocampus), Abstract — Full Text
- Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a): T. Homma, et al.; Behav. Brain Res. 22, 319 (2016), Sample Type: Mouse plasma, Abstract
- Serotonin Activates Bacterial Quorum Sensing and Enhances the Virulence of Pseudomonas aeruginosa in the Host: L.D. Knecht, et al.; EBioMedicine 9, 161 (2016), Sample Type: Mouse Feces and tissue lysate (Intestine), Abstract
- Use of the RatLoft decreases pup mortality in lactating mice: S.R. Weaver, et al.; Lab. Anim. 50, 370 (2016), Sample Type: Mouse serum, Abstract
- Generation of functional human serotonergic neurons from fibroblasts: K.C. Vadodaria, et al.; Mol. Psychiatry 21, 49 (2016), Sample Type: Human Culture supernatant (iNs and ISNs cells), Abstract
- Unveiling the interactions among BMPR-2, ALK-1 and 5-HTT genes in the pathophysiology of HAPE: Z. Ali, et al.; Gene 588, 163 (2016), Sample Type: Human plasma, Abstract
- Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production: A. Houlden, et al.; Brain. Behav. Immun. 57, 10 (2016), Sample Type: Mouse tissue lysate (Intestine), Abstract
- Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt: A. Wannhoff, et al.; Aliment. Pharmacol. Ther. 43, 955 (2016), Sample Type: Human other (Blood), Abstract — Full Text
- FLUID AND ION SECRETION BY MALPIGHIAN TUBULES OF LARVAL CHIRONOMIDS, Chironomus riparius: EFFECTS OF REARING SALINITY, TRANSPORT INHIBITORS, AND SEROTONIN: Zadeh-Tahmasebi, M., Bui, P., et al.; Arch. Insect Biochem. Physiol. 93, 67 (2016), Sample Type: Insect (Harlequin fly [Chironomus riparius]) other (larval hemolymph), Abstract
- Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis: T.H. Yang, et al.; Arthritis Res. Ther. 17, 364 (2015), Sample Type: Mouse serum, Abstract — Full Text
- Human tear serotonin levels correlate with symptoms and signs of dry eye: P. Chhadva, et al.; Ophthalmology 122, 1675 (2015), Sample Type: Human other (Tear), Abstract
- Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes: H. Bennet, et al.; Peptides 71, 113 (2015), Sample Type: Human cell lysate (Islets of Langherans), Abstract
- Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer: P. Dowling, et al.; Clin. Chim. Acta 441, 133 (2015), Sample Type: Human plasma, Abstract
- Leptin, adiponectin and serotonin levels in lean and obese dogs: H.J. Park, et al.; BMC Vet. Res. 10, 113 (2014), Sample Type: Canine (Dog) plasma, Abstract — Full Text
- Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling: J. Laporta, et al.; Mol. Endocrinol. 28, 1866 (2014), Sample Type: Mouse serum and tissue lysate (Mammary gland), Abstract
- Peripheral Serotonin Regulates Maternal Calcium Trafficking in Mammary Epithelial Cells during Lactation in Mice: J. Laporta, et al.; PLoS One 9, e110190 (2014), Sample Type: Mouse serum and tissue lysate (Mammary gland), Abstract — Full Text
- Short communication: Circulating serotonin (5-HT) concentrations on day 1 of lactation as a potential predictor of transition-related disorders: J. Laporta, et al.; J. Dairy Sci. 96, 5146 (2013), Sample Type: Cow serum and plasma, Abstract
- Serotonin (5-HT) affects expression of liver metabolic enzymes and mammary gland glucose transporters during the transition from pregnancy to lactation: J. Laporta, et al.; PLoS One 8, e57847 (2013), Sample Type: Rat serum and tissue lysate (Liver, Mammary gland), Abstract — Full Text
- Feeding 5-hydroxy-l-tryptophan during the transition from pregnancy to lactation increases calcium mobilization from bone in rats: J. Laporta, et al.; Domest. Anim. Endocrinol. 44, 176 (2013), Sample Type: Rat serum and tissue lysate (Mammary gland), Abstract
- Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats: R. Valladares, et al.; FASEB J. 27, 1711 (2013), Sample Type: Rat serum, Abstract
- Perinatal growth restriction is not related to higher intestinal distribution and increased serum levels of 5-hydroxytryptamin in piglets: S. Willemen, et al.; J. Anim. Sci. 90S4, 305 (2012), Sample Type: Pig serum, Abstract
- Static and cyclic tensile strain induce myxomatous effector proteins and serotonin in canine mitral valves: C.M. Lacerda, et al.; J. Vet. Cardiol. 14, 223 (2012), Sample Type: Canine (Dog) Culture Supernatant (Mitral valve), Abstract
- Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves: C.M. Lacerda, et al.; Am. J. Physiol. Heart Circ. Physiol. 302, H1983 (2012), Sample Type: Sheep Culture Supernatant (Mitral valve), Abstract
- Tryptophan hydroxylase-1 regulates immune tolerance and inflammation: E.C. Nowak, et al.; J. Exp. Med. 209, 2127 (2012), Sample Type: Mouse serum, Abstract — Full Text
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