SCREEN-WELL® Nephrotoxicity library

The SCREEN-WELL® Nephrotoxicity Library is a focused collection of 86 compounds with defined and diverse nephrotoxicity, including analgesic nephropathy, interstitial nephritis, glomerularopathy, proximal and distal tubulopathy, acute renal failure, chronic kidney disease, and more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. Most of the compounds are dissolved in DMSO at 10mM unless otherwise stated in the documentation provided with the library. Selected compounds are dissolved in DI water. All compounds are provided at 100 µl volumes in a 96-well plate. This library is an essential cost-effective tool for predictive toxicology screening and assay development.