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SCREEN-WELL® Kinase Inhibitor library

BML-2832

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Manual
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The SCREEN-WELL^® Kinase Inhibitor Library contains 80 known kinase inhibitors of well-defined activity. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library is an ideal tool for chemical genomics, assay development and other pharmacological applications. Includes inhibitors of these important kinases: Insulin/IGF Receptors, PI 3-Kinase, CaM Kinase II, JAK, PKA, CDK, JNK, PKC, CKI II, MAPK, RAF, EGFR, MEK, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR and many more.

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Product Details

Application	HTS
Concentration	10mM
Contents	80 compounds including inhibitors of these important kinases: BTK, CaM Kinase, CDK, CKI & II, EGFR, GSK, IKK, Insulin receptor, JAK, JNK, MAPK, MEK, MLCK, PI 3-Kinase, PDGFR, PKA, PKC, RAF, SAPK, Src-family, VEGFR, and more.
Formulation	DMSO solutions.
Quantity	100µl or 500µl per well

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least one year from the date of receipt when stored at -80°C.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

AKT1 as a therapeutic target for platinum-resistant SOX2 positive ovarian cancer cells: Xue, M., Kang, L., et al.; Sci. Rep. 15, 15096 (2025), Abstract
Variola Virus and Clade I Mpox Virus Differentially Modulate Cellular Responses Longitudinally in Monocytes During Infection: V. Wahl, et al.; J. Infect. Dis. 229, S265 (2024), Abstract
Novel inhibitors of microtubule organization and phragmoplast formation in diverse plant species: Y. Kimata, et al.; Life Sci. Alliance 6, e202201657 (2023), Abstract
Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction: S. Giacosa, et al.; Cancers 13, 576 (2023), Abstract
A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma: Beri, P., Plunkett, C., et al.; APL Bioeng. 7, 026104 (2023), Abstract
High Resolution Crystal Structure and Chemical Screening Reveal Pantothenate Kinase as a New Target for Antifungal Development: S. Gihaz, et al.; Structures 30, 1494 (2022), Abstract
Phosphorylation of RNA polymerase II by CDKC; 2 maintains the Arabidopsis circadian clock period: T.N. Uehara, et al.; Plant Cell Physiol. 63, 450 (2022), Abstract — Full Text
Nephrotoxicity of calcineurin inhibitors in kidney epithelial cells is independent of calcineurin and NFAT signaling: A. Karolin, et al.; Front. Pharmacol. 12, 789080 (2022), Abstract — Full Text
Large-scale identification of multiple classes of host defense peptide-inducing compounds for antimicrobial therapy: W. Lyu, et al.; Int. J. Mol. Sci. 23, 8400 (2022), Abstract — Full Text
BML-257, a small molecule that protects against drug induced liver injury in zebrafish: U. Jagtap, et al.; Chem. Res. Toxicol. 35, 1393 (2022), Abstract