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SCREEN-WELL® Ion Channel ligand library

BML-2805

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The SCREEN-WELL^® Ion Channel Ligand Library contains 70 ion channel blockers and openers for use in characterizing and identifying ion channels in individual cells or tissue.

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Product Details

Application	HTS
Concentration	10mM in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least one year from the date of receipt when stored at -80°C.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Defining the Polycystin Pharmacophore Through HTS & Computational Biophysics: Guadarrama, E., Vanoye, C. G., et al.; bioRxiv , (2025)
Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish: B.P. Sampurna, et al.; Cells 8, 566 (2019), Abstract — Full Text
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation: M. Segovia, et al.; Cancer Cell 35, 767 (2019), Abstract — Full Text
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy: Y. Chen, et al.; Sci. Rep. 7, 45366 (2017), Abstract
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest. 127, 2739 (2017), Abstract — Full Text
A KNIME-based analysis of the zebrafish photomotor response clusters the phenotypes of 14 classes of neuroactive molecules: D. Copmans, et al.; J. Biomol. Screen. 21, 427 (2016), Abstract
An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines: M. Burnette, et al.; Mol. Biosyst. 10, 2713 (2014), Abstract — Full Text
Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer’s disease: K. Honarnejad, et al.; PLoS One 8, e80645 (2013), Abstract — Full Text
Cardiac glycosides are potent inhibitors of interferon-β gene expression: J. Ye, et al.; Nat. Chem. Biol. 7, 25 (2011), Abstract — Full Text
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov, et al.; PNAS 105, 11218 (2008), Abstract

Datasheet, Manuals, SDS & CofA

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SCREEN-WELL® Ion Channel ligand library

BML-2805

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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