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SCREEN-WELL® Bioactive lipid library

BML-2800

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The SCREEN-WELL^® Bioactive Lipid Library contains 190 bioactive lipids in a 96 well format. Ideal for screening or identifiying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays and for routine pharmacological applications.

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Product Details

Application	HTS
Concentration	DMSO solutions (1.0 or 0.1mM, depending on compound).
Contents	190 compounds including: Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, HETEs deHETEs, hepoxilins, Polyunsaturated fatty acids, Leukotrienes, lipoxins, LPA & phosphatidic acids, Octadecanoids, PAFs, Prostaglandins & thromboxanes, Retinoids, vitamin D metabolites, Sphingolipids.
Quantity	100 or 500µl per well.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least one year from the date of receipt when stored at -80°C.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Molecular basis for the interaction of cellular retinol-binding protein 2 (CRBP2) with non-retinoid ligands: J. Silvaroli, et al.; J. Lipid Res. 62, 100054 (2021), Abstract
Mechanism of activation for the sirtuin 6 protein deacylase: M.A. Klein, et al.; J. Biol. Chem. 295, 1385 (2020), Abstract — Full Text
Abnormal cannabidiol modulates vitamin A metabolism by acting as a competitive inhibitor of CRBP1: J.A. Silvaroli, et al.; ACS Chem. Biol. 14, 434 (2019), Abstract — Full Text
Brown Adipogenic Reprogramming Induced by a Small Molecule: B. Nie, et al.; Cell Rep. 18, 624 (2017), Abstract
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest. 127, 2739 (2017), Abstract — Full Text
Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells: J.H. Rhim, et al.; Sci. Rep. 6, 26547 (2016), Abstract — Full Text
Targeting surface voids to counter membrane disorders in lipointoxication-related diseases: R. Ferru-Clément, et al.; J. Cell. Sci. 129, 2368 (2016), Abstract
AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells: T. Yoshinaga, et al.; PLoS One 11, e0167848 (2016), Abstract — Full Text
Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans: P.R. Rodrigues, et al.; G3 (Bethesda) 6, 1695 (2016), Abstract — Full Text
The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication: M. Carocci, et al.; Antimicrob. Agents Chemother. 59, 85 (2015), Abstract — Full Text

Datasheet, Manuals, SDS & CofA

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SCREEN-WELL® Bioactive lipid library

BML-2800

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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