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Modulator of both agonist and antagonist binding to G protein-coupled receptors which functions via thiol modification rather than true allosteric mechanisms. Has been shown to block agonist or antagonist activity at adenosine, adrenergic, dopaminergic, muscarinic, opioid and P2Y. IC50s vary from 0.1 to 1.8µM.The nature of the interaction of SCH-202676 and receptors is dependent on whether it is studied using intact versus broken cell preparations.
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| Regulatory Status |
RUO – Research Use Only |
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