SANT-1

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Potent, cell-permeable antagonist of the Shh signaling pathway.

Equipotently inhibits the activities of both wild-type and oncogenic Smoothened.

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Alternative Name	Shh signaling antagonist V, (E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenylpyrazol-4-yl)methanimine
Appearance	White crystalline solid.
CAS	304909-07-7
Couple Target	Smoothened
Couple Type	Inhibitor
Formula	C₂₃H₂₇N₅
MW	373.5
Purity	≥99% (HPLC)
Solubility	Soluble in DMSO or ethanol.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Short Term Storage	-20°C
Long Term Storage	-80°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

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