Sample Deproteinizing Kit (PCA)

It is a fundamental requirement in biochemistry and related fields to be able to remove those constituents of the sample under investigation which will interfere with analysis in any of several ways, both physical and chemical. When the analyte in question is a small molecule, the presence of macromolecules such as proteins, nucleic acids and carbohydrates can seriously impair analysis. Proteins are usually removed by precipitation using one of several chemicals including acetone, perchloric acid (PCA), metaphosphoric acid, sulfosalicylic acid or trichloroacetic acid. PCA is a strong acid commonly used for protein precipitation and removal in biological samples. AkrivisBio’s Deproteinizing Sample Preparation Kit utilizes a PCA precipitation method, providing a unique tool to prepare samples for the analysis of a variety of small molecules such as lipids, metabolites etc.