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S-Farnesyl-L-cysteine methyl ester

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Multidrug resistance transporter activator

Stimulates the multidrug resistance transporter ATPase activity (4-5-fold at 10-20 µM) and competes for drug binding.

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Appearance	Colorless oil.
CAS	125741-64-2
Couple Target	Multidrug resistance transporter
Couple Type	Activator
Formula	C₁₉H₃₃NO₂S
MW	339.5
Purity	≥98% (TLC)
Solubility	Soluble in DMSO (25 mg/ml) and ethanol (25 mg/ml).
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions under an inert atmosphere in solvent that has been purged with nitrogen or argon at -20°C for up to one month.
Long Term Storage	-20°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Interaction of prenylcysteine methyl esters with the multidrug resistance transporter: L. Zhang, et al.; J. Biol. Chem. 269, 15973 (1994), Abstract — Full Text

Last modified: May 29, 2024

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