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RWJ-60475 (AM)₃

BML-PR110

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CD45 inhibitor

RWJ-60475-(AM)₃ is a cell-permeable acetoxymethyl (AM) ester of RWJ-60475. The AM esters confer cell membrane permeability and are hydrolyzed by intracellular esterases, trapping the active inhibitor within the cell. The IC₅₀ for the hydrolyzed, active inhibitor is 2 µM.

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Product Details

Appearance	Pale yellow-brown oil.
Couple Target	CD45, PTP
Couple Type	Inhibitor
Formula	C₂₂H₂₃BrNO₁₃P
MW	620.4
Purity	≥95% (HPLC)
Solubility	Soluble in DMSO (25 mg/ml), acetone, or dimethylchloride.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Make solutions fresh daily.
Handling	Protect from moisture.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

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RWJ-60475 (AM)₃

BML-PR110

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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