RPA

Fluorescent non-toxic iron sensor (Ex(max): 564nm; Em(max): 601nm), which allows to determine the iron pool specifically in single intact mitochondria. Tool to assess the function of labile (“redox-active”) iron, e.g. in processes of cell and tissue injury where free radicals are considered to be involved. Intramitochondrial RPA fluorescence is quenched when iron is added to cells in a membrane-permeant form.