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Roquefortine C

ALX-350-342

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Cytochrome P450 inhibitor

Potent neurotoxin produced by a diverse range of fungi, most notably Penicillium species. Inhibits growth of Gram-positive bacteria. Inhibits cytochrome p450.

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Product Details

Appearance	White to off-white solid.
CAS	58735-64-1
Couple Target	Cytochrome P450
Couple Type	Inhibitor
Formula	C₂₂H₂₃N₅O₂
MW	389.5
Purity	≥95% (HPLC)
RTECS	UQ4730500
Solubility	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
Source	Isolated from MST-FP1764.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Toxigenic potentiality of Aspergillus flavus and Aspergillus parasiticus strains isolated from black pepper assessed by an LC-MS/MS based multi-mycotoxin method: P. Yogendrarajah; Food Microbiol. 52, 185 (2015), Application(s): Cell culture , Abstract
The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia 158, 317 (2004), Abstract
Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol. 14, 1259 (2001), Abstract
Inhibitory effects of roquefortine on hepatic cytochromes P450: C. Aninat and M. Delaforge; Adv. Exp. Med. Biol. 500, 331 (2001), Abstract
Antimicrobial action of roquefortine: B. Kopp-Holtwiesche and H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol. 10, 41 (1990), Abstract
Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975)

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Roquefortine C

ALX-350-342

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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