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Resibufogenin

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Na⁺/K⁺ ATPase inhibitor

Specific Na⁺/K⁺-ATPase inhibitor.

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Alternative Name	(3β,5β,15β)-14,15-Epoxy-3-hydroxy-5-bufa-20,22-dienolide
Appearance	White to off-white solid.
CAS	465-39-4
Couple Target	ATPase
Couple Type	Inhibitor
Formula	C₂₄H₃₂O₄
Identity	Determined by MS.
MI	14: 8146
MW	384.5
Purity	≥98% (HPLC)
RTECS	EI2975000
Solubility	Soluble in chloroform.
Source	Isolated from Bufonis venom.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Resibufogenin corrects hypertension in a rat model of human preeclampsia: H. Vu, et al.; Exp. Biol. Med. (Maywood) 231, 215 (2006), Abstract
Effects of resibufogenin from toad venom on isolated Purkinje fibers: J.T. Xie, et al.; Am. J. Chin. Med. 28, 187 (2000), Abstract

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