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Ras polyclonal antibody

ADI-KAP-GP001

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Monomeric G-protein Ras functions as a molecular switch linking receptor and nonreceptor tyrosine kinase activation to a number of downstream signaling pathways. Oncogenic mutations, which occur in approximately 30% of all cases of human cancer, lead to the stimulation of proliferation and the inhibition of apoptosis.

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This antibody is covered by our Worry-Free Guarantee.

Ras polyclonal antibody Western blot — Western blot analysis of anti-Ras pAb: Lane 1: MW marker, Lane 2: HeLa lysate, Mouse Brain Lysate, Rat Brain Lysate.

Product Details

Application	WB
Application Notes	Detects a band of 21-23kDa by Western blot.
Formulation	Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
GenBank ID	J00277
Host	Rabbit
Immunogen	Synthetic peptide corresponding to a portion of human Ras.
Purity Detail	Protein A affinity purified.
Recommendation Dilutions/Conditions	Western Blot (1:500, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from rabbit serum.
Species Reactivity	Bovine, Human, Mouse, Rat
UniProt ID	P01112
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity: Echeverría, P. C., Bhattacharya, K., et al.; PLoS One 14, e0208287 (2019), Abstract