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Rac1 inhibitor

ENZ-CHM116

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Cell-permeable, reversible, and selective Rac1 inhibitor.

NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth.

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Product Details

Alternative Name	N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Appearance	White powder solid.
CAS	733767-34-5
Couple Target	Rac
Couple Type	Inhibitor
Formula	C₂₄H₃₅N₇ . 3 HCl
MW	531
Purity	≥99% (HPLC)
Solubility	Soluble in water.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Short Term Storage	-20°C
Long Term Storage	-80°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Non-Genomic AhR-Signaling Modulates the Immune Response in Endotoxin-Activated Macrophages After Activation by the Environmental Stressor BaP: H. Großkop, et al.; Front. Immunol. 12, 620270 (2021), Abstract — Full Text
Nanosecond pulsed current under plasma-producing conditions induces morphological alterations and stress fiber formation in human fibrosarcoma HT-1080 cells: C.H. Chang, et al.; Arch. Biochem. Biophys. 681, 108252 (2020), Abstract
The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes: Nogalski, M. T., Chan, G. C., et al.; PLoS Pathog. 9, e1003463 (2013), Application(s): In Vitro, Abstract

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Rac1 inhibitor

ENZ-CHM116

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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