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R-(-)-Glucoraphanin . potassium salt

ALX-350-181

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Cytochrome P450 modulator

Modulator of hepatic cytochrome P450 and phase II conjugation activity. The enzyme myrosinase transforms R-(-)-glucoraphanin into R-Sulforaphane (Prod. No. ALX-350-230).

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Product Details

Alternative Name	4-Methylsulfinylbutylglucosinate . K
Appearance	White solid.
CAS	21414-41-5
Couple Target	Cytochrome P450
Formula	C₁₂H₂₂NO₁₀S₃ . K . xH₂O
MW	436.5 . 39.1 (anhydrous basis)
Purity	≥99% (HPLC)
Source	Isolated from Brassica oleracea var. palmifolia

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Very hygroscopic.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables: A.F. Abdull Razis, et al.; Toxicology 277, 74 (2010), Abstract
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice: A.T. Dinkova-Kostova, et al.; Photochem. Photobiol. Sci. 9, 597 (2010), Abstract
Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products: M. Haack, et al.; Biol. Chem. 391, 1281 (2010), Abstract
Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin: R.H. Lai, et al.; Food Chem. Toxicol. 46, 195 (2008), Abstract

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R-(-)-Glucoraphanin . potassium salt

ALX-350-181

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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