Home Shop Purinergic receptor P2X7 (mouse) monoclonal antibody (HANO43)

Purinergic receptor P2X7 (mouse) monoclonal antibody (HANO43)

ALX-802-027

9 citations

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Product Details

Alternative Name	P2X purinoceptor 7, P2RX7
Application	Flow Cytometry, ICC, IP
Clone	HANO43
Formulation	Liquid. Hybridoma supernatant containing 0.02% sodium azide.
Host	Rat
Immunogen	Vector containing the cDNA of mouse purinergic receptor P2X7.
Isotype	IgG2b
Positive Control	HEK cells transfected with an expression plasmid for mouse purinergic receptor P2X7 can be used as positive control.
Recommendation Dilutions/Conditions	Flow Cytometry (1:1-1:10)Immunocytochemistry (1:1-1:10)Immunoprecipitation (1:1-1:10)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Mouse
UniProt ID	Q9Z1M0
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Animal Models for the Investigation of P2X7 Receptors: Sluyter, R., Adriouch, S., et al.; Int. J. Mol. Sci. 24, (2023), Abstract
Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages: S. Bidula, et al.; Cell Death Dis. 10, 882 (2019), Abstract — Full Text
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.: Pearlman, E., Karmakar, M., et al.; Nat. Commun. 7, 10555 (2016), Application(s): ICC-IF / Reactant(s): Human, Mouse, Abstract
Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice: Y.G. Chen, et al.; J. Immunol. 186, 4278 (2011), Abstract
Murine epidermal Langerhans cells and keratinocytes express functional P2X7 receptors: J.N. Tran, et al.; Exp. Dermatol. 19, e151 (2010), Abstract — Full Text
Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation: S. Möller, et al.; Purinergic Signal. 3, 359 (2007), Abstract — Full Text
ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site: S. Adriouch, et al.; FASEB J. 22, 861 (2007), Abstract — Full Text
P2X7 receptor expression levels determine lethal effects of a purine based danger signal in T lymphocytes: F. Aswad & G. Dennert; Cell. Immunol. 243, 58 (2006), Abstract
Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization: S. Adriouch, et al.; Cell. Immunol. 236, 72 (2005), Abstract

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Purinergic receptor P2X7 (mouse) monoclonal antibody (HANO43)

ALX-802-027

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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