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[pThr232]Aurora B polyclonal antibody

ADI-KAP-CC203

  • ADI-KAP-CC203-D   —   50 µg
    $291.00
  • ADI-KAP-CC203-F   —   200 µg
    $543.00

Aurora A, B, and C have emerged as key mitotic regulators of mammalian centrosome function, chromosome segregation and cytokinesis. Aurora B is one of several chromosomal passenger proteins involved in chromosome alignment at the metaphase plate and cytokinesis. Phosphorylation of a threonine residue in the Aurora activation loop (Thr232 in human Aurora B) is believed to be an essential regulatory mechanism in Aurora kinase activation.

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Regulatory Status

RUO – Research Use Only