Home Shop [pSer52]Eukaryotic Initiation factor 2 α polyclonal antibody

[pSer⁵²]Eukaryotic Initiation factor 2 α polyclonal antibody

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This antibody is covered by our Worry-Free Guarantee.

Alternative Name	eIF2α
Application	WB
Crossreactivity	Does not cross-react with the unphosphorylated form of eIF2α.
Formulation	Liquid. In Dulbecco’s PBS, pH 7.3, containing 1mg/ml BSA, 50% glycerol and 0.05% sodium azide.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to a portion of human eIF2α (eukaryotic initiation factor-2α) phosphorylated at Ser51(Ser52 in mouse).
Recommendation Dilutions/Conditions	Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Human, Mouse, Yeast
Specificity	Recognizes human and yeast eIF2α phosphorylated at Ser⁵¹ and mouse eIF2α phosphorylated at Ser⁵².
UniProt ID	P05198
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Aβ42 induces stress granule formation via PACT/PKR pathway: Ramasamy, V. S., Nathan, A. B. P., et al.; Sci. Rep. 15, 5829 (2025), Application(s): WB / Reactant(s): Human, Abstract
The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition: Martin, J. L., Terry, S. J., et al.; J. Cell Sci. 136, (2023), Abstract
TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes.: Rader, D. J., Tobias, J. W., et al.; J. Clin. Invest. 131, (2021), Application(s): WB / Reactant(s): Mouse, Abstract
Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside: M.J. Virgolini, et al.; Biochim. Biophys. Acta Mol. Cell Res. 1866, 225 (2019), Abstract
Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.: Clarke, J. R., Lyra E Silva, N. M., et al.; EMBO Mol. Med. 7, 190 (2015), Application(s): ICC, IHC, WB / Reactant(s): Mouse, Abstract
The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R.: Akira, S., Boonyaratanakornkit, J., et al.; J. Virol. 85, 1495 (2011), Application(s): WB / Reactant(s): Human, Abstract

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