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This antibody is covered by our Worry-Free Guarantee.
![[pSer52]Eukaryotic Initiation factor 2 α polyclonal antibody image Western Blot](https://www.enzo.com/wp-content/uploads/2023/01/bml-sa405.gif?w=121)
Mouse 3T3 cell extracts were blotted and incubated with anti-eIF2-α (pS52) antibody following (1) prior incubation in the presence of the peptide immunogen, (2) the nonphosphopeptide corresponding to the eIF2-α (pS51) phosphopeptide, (3) or no peptide. Only the phospho-peptide corresponding to the region surrounding serine 51 (serine 52 in mouse) blocks the antibody signal.
![[pSer52]Eukaryotic Initiation factor 2 α polyclonal antibody image Western Blot](https://www.enzo.com/wp-content/uploads/2023/01/bml-sa405.gif?w=121)
Product Details
Alternative Name |
eIF2α |
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Application |
WB |
Crossreactivity |
Does not cross-react with the unphosphorylated form of eIF2α. |
Formulation |
Liquid. In Dulbecco’s PBS, pH 7.3, containing 1mg/ml BSA, 50% glycerol and 0.05% sodium azide. |
Host |
Rabbit |
Immunogen |
Synthetic peptide corresponding to a portion of human eIF2α (eukaryotic initiation factor-2α) phosphorylated at Ser51(Ser52 in mouse). |
Recommendation Dilutions/Conditions |
Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
Species Reactivity |
Human, Mouse, Yeast |
Specificity |
Recognizes human and yeast eIF2α phosphorylated at Ser51 and mouse eIF2α phosphorylated at Ser52. |
UniProt ID |
P05198 |
Worry-free Guarantee |
This antibody is covered by our Worry-Free Guarantee. |
Handling & Storage
Handling |
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. |
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Long Term Storage |
-80°C |
Shipping |
Dry Ice |
Regulatory Status |
RUO – Research Use Only |
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- Aβ42 induces stress granule formation via PACT/PKR pathway: Ramasamy, V. S., Nathan, A. B. P., et al.; Sci. Rep. 15, 5829 (2025), Application(s): WB / Reactant(s): Human, Abstract
- The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition: Martin, J. L., Terry, S. J., et al.; J. Cell Sci. 136, (2023), Abstract
- TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes.: Rader, D. J., Tobias, J. W., et al.; J. Clin. Invest. 131, (2021), Application(s): WB / Reactant(s): Mouse, Abstract
- Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside: M.J. Virgolini, et al.; Biochim. Biophys. Acta Mol. Cell Res. 1866, 225 (2019), Abstract
- Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.: Clarke, J. R., Lyra E Silva, N. M., et al.; EMBO Mol. Med. 7, 190 (2015), Application(s): ICC, IHC, WB / Reactant(s): Mouse, Abstract
- The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R.: Akira, S., Boonyaratanakornkit, J., et al.; J. Virol. 85, 1495 (2011), Application(s): WB / Reactant(s): Human, Abstract
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SDS
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