Home Shop [pSer239]VASP monoclonal antibody (16C2) (FITC conjugate)

[pSer239]VASP monoclonal antibody (16C2) (FITC conjugate)

ALX-804-240F

9 citations

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This antibody is covered by our Worry-Free Guarantee.

Product Details

Alternative Name	Vasodilator stimulated phosphoprotein
Application	Flow Cytometry, ICC
Clone	16C2
Crossreactivity	Does not cross-react with the non-phosphorylated form of VASP.
Formulation	Liquid. 0.5mg/ml in 2x PBS containing 0.09% sodium azide, PEG and sucrose.
Host	Mouse
Immunogen	Synthetic peptide corresponding to a portion of VASP (vasodilator stimulated phosphoprotein) phosphorylated at Ser239 (RKVpSKQE) conjugated to KLH.
Isotype	IgG1
Purity Detail	Thiophilic adsorption and size exclusion chromatography purified.
Recommendation Dilutions/Conditions	Immunocytochemistry (use at 1-10µg/ml; may tolerate 0.5% formaldehyde fixation)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Human, Mouse, Rabbit, Rat
Specificity	Recognizes Ser²³⁹-phosphorylated VASP.
Technical Info / Product Notes	Important! The use of MAb to VASP (activated) (Ser²³⁹) (16C2) for diagnostic or therapeutic purposes is patented! The antibody is supplied for research use only!
UniProt ID	P50552
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.
Handling	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Platelet Priming and Activation in Naturally Occurring Thermal Burn Injuries and Wildfire Smoke Exposure Is Associated With Intracardiac Thrombosis and Spontaneous Echocardiographic Contrast in Feline Survivors.: Tan, A. W. K., Li, R. H. L., et al.; Front. Vet. Sci. 9, 892377 (2022), Application(s): FC/FACS, Abstract
A genetic polymorphism in P2RY1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy.: Court, M. H., Stern, J. A., et al.; Sci. Rep. 11, 12522 (2021), Application(s): FC/FACS, Abstract
Genetic Polymorphisms Impact Response to Clopidogrel in Feline Hypertrophic Cardiomyopathy: Ueda, Y., Li, R., et al.; Research Square , (2021)
Assessment of P2Y12 Inhibition by Clopidogrel in Feline Platelets Using Flow Cytometry Quantification of Vasodilator-Stimulated Phosphoprotein Phosphorylation: R.H.L. Li, et al.; Front. Vet. Sci. 7, 267 (2020), Abstract
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets: J.A. Rosado, et al.; J. Biol. Chem. 276, 15666 (2001), Abstract — Full Text
Effects of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl Cyclase and cGMP-Dependent Protein Kinase and Their Downstream Target Vasodilator-Simulated Phosphoprotein in Aorta: A. Mülsch, et al.; Circulation 103, 2188 (2001), Abstract — Full Text
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells: M. Burkhardt, et al.; J. Biol. Chem. 275, 33536 (2000), Abstract — Full Text
Flow cytometry analysis of intracell. VASP phosphorylation for the assessment of activating and inhibitory signal transduct. pathways in human platelets-definition & detect. of ticlopidine/clopidogrel: U.R. Schwarz, et al.; Thromb. Haemost. 82, 1145 (1999), Abstract
Analysis and Regulation of Vasodilator-stimulated Phosphoprotein Serine 239 Phosphorylation in Vitro and in Intact Cells Using a Phosphospecific Monoclonal Antibody: A. Smolenski, et al.; J. Biol. Chem. 273, 20029 (1998), Abstract — Full Text

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[pSer239]VASP monoclonal antibody (16C2) (FITC conjugate)

ALX-804-240F

Product Details

Handling & Storage

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