Home Shop Proteasome 20S α4 subunit monoclonal antibody (MCP79)

Proteasome 20S α4 subunit monoclonal antibody (MCP79)

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Alternative Name	Proteasome subunit α type-7, Proteasome subunit RC6-1, Proteasome subunit XAPC7
Application	IHC, WB
Application Notes	Does not work in IP.
Clone	MCP79
Formulation	Liquid. Ascites in TBS, containing 5 mM sodium azide.
Gene/Protein Identifier	PSMA7 (gene name)
Host	Mouse
Immunogen	Human placenta derived proteasomes.
Isotype	IgG1
Source	Purified from hybridoma tissue culture supernatant.
Species Reactivity	Human, Mouse
Specificity	Recognizes the α4 subunit of the 20S proteasome.
Technical Info / Product Notes	Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from “standard” nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.
UniProt ID	O14818
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Regulatory Status	RUO – Research Use Only

The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes: Eibach, Y., Kreher, S., et al.; Sci. Adv. 11, eado3852 (2025), Abstract
High glucose leads to redistribution of the proteasomal system.: Grune, T., Schnell, V., et al.; Biofactors 49, 636 (2023), Application(s): ICC / Reactant(s): Human, Abstract
Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis: F. Cerruti, et al.; Sci. Rep. 7, 17626 (2017), Abstract — Full Text
Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study: E. Laudermilch, et al.; Mol. Biol. Cell 27, 3964 (2016), Application(s): Immunoblotting and Immunofluorescence microscopy, Abstract — Full Text
Possible role of ZPAC, zygote-specific proteasome assembly chaperone, during spermatogenesis in the mouse.: Kato, H., Mitani, T., et al.; J. Reprod. Dev. 60, 179 (2014), Application(s): IHC / Reactant(s): Mouse, Abstract

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