Home Shop Proteasome 20S α2 subunit monoclonal antibody (MCP21)

Proteasome 20S α2 subunit monoclonal antibody (MCP21)

BML-PW8105

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Proteasome 20S α2 subunit monoclonal antibody (MCP21) Western blot — Western blot analysis of Proteasome 20S α2 subunit, mAb (MCP21) (Prod. No. BML-PW8105): Lane 1: MW marker, Lane 2: HeLa (heat shocked) (Prod. No. ADI-LYC-HL101), Lane 3: Jurkat (Prod. No. ADI-LYC-JK100), Lane 4: HeLa S100 fraction (Prod. No. BML-SW8750), Lane 5: Proteasome 26S (human), (purified) (Prod. No. BML-PW9310).

Product Details

Alternative Name	Proteasome subunit α type-2, Macropain subunit C3
Application	IHC, IP, WB
Clone	MCP21
Formulation	Liquid. In PBS containing 10mM sodium azide.
Gene/Protein Identifier	PSMA2 (gene name)
Host	Mouse
Immunogen	Human placenta derived proteasomes.
Isotype	IgG1
Purity Detail	Partially purified ascites.
Source	Purified from mouse ascites.
Species Reactivity	Bovine, Human, Rabbit
Specificity	Recognizes the α2 subunit of the 20S proteasome.
Technical Info / Product Notes	Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from “standard” nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.
UniProt ID	P25787
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Simulating the conformational dynamics of the ATPase complex on proteasome using its free-energy landscape: Fang, R., Lu, Y., et al.; STAR Protoc. 4, 102182 (2023), Abstract
NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses: Corridoni, D., Shiraishi, S., et al.; Front. Immunol. 10, 958 (2019), Abstract
Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome.: Lupski, J. R., Gibbs, R. A., et al.; Am. J. Hum. Genet. 102, 1126 (2018), Application(s): WB / Reactant(s): Human, Abstract
Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease: A. Armstrong, et al.; Neuromolecular Med. 16, 150 (2014), Application(s): WB / Reactant(s) Human, Abstract — Full Text
TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions: Z. Lukic, et al.; Retrovirology 8, 93 (2011), Abstract — Full Text

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Proteasome 20S α2 subunit monoclonal antibody (MCP21)

BML-PW8105

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Proteasome 20S α2 subunit monoclonal antibody (MCP21)

BML-PW8105

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