Lab Essentials
AMPIVIEW® RNA probes
Enabling Your Projects 
GMP Services
Bulk Solutions
Research Travel Grant
Have You Published Using an Enzo Product?
pppTpT has been identified as a bacterial signalling nucleotide involved in a bacterial anti-phage defence system named Clover. In the Clover system, elevated TTP (aka dTTP) levels during viral infection activate the dGTPase function of the Clover protein CloA which depletes the cellular nucleotide pool, thereby restricting phage replication. The partnering regulatory enzyme CloB produces the inhibitory signal pppTpT that suppresses CloA activation and thus protects uninfected cells from aberrant nucleotide depletion and immune-associated toxicity.
Shipping: Available products typically ship within 24/48h, via priority shipping.
Do you need support? Contact Customer Service or Technical Support.
Online Account
Access or Create Your Account
| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | 5′-Triphosphoadenylyl-(3’→5′)-adenosine . sodium salt |
|---|---|
| CAS | 17730-98-2 |
| Couple Type | Modified nucleotides |
| Purity | > 95% HPLC |
ppTpT
BLG-D259
Nucleoside bisphosphate suitable for the characterisation of ribonucleases and nucleotidases
| Alternative Name | 5′-Diphosphothymidylyl-(3’→5′)-thymidine . sodium salt, p2diT |
|---|---|
| CAS | 27821-51-8 |
| Couple Type | Modified nucleotides |
| Purity | > 95 % HPLC |
pTpT
BLG-P129
Nucleoside bisphosphate suitable for the characterisation of ribonucleases and nucleotidases
| Alternative Name | 5′-Phosphothymidylyl-(3’→5′)-thymidine . sodium salt, p1diT, 5′-pTpT |
|---|---|
| CAS | 10360-48-2 |
| Couple Type | Modified nucleotides |
| Purity | > 95 % HPLC |