pppApG

In pppApG a 5′-ATP unit is connected with a 5′-GMP unit via a 3′ → 5′ linkage to form a linear dinucleotide. pppApG is a potential endogenous metabolite of the metazoan second messenger 2′,3′-cGAMP (c[G(2′,5′)pA(3′,5′)p], Prod. No. BLG-C161) and/or of the bacterial signalling nucleotide 3′,3′-cGAMP (c-(ApGp), Prod. No. BLG-C117). pppApG was reported to be the linear dinucleotide intermediate in the enzymatic production of 3′,3′-cGAMP by the Vibrio cholerae pathogenicity factor DncV.

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