In pppA(2′,5′)pG a 5′-ATP unit is connected with a 5′-GMP unit via a 2′ → 5′ linkage to form a linear dinucleotide. pppA(2′,5′)pG is the linear intermediate in the two-step enzymatic production of 3′,2′-cGAMP (Cat. No. C 238) by the Drosophila melanogaster enzyme cGLR1 in response to dsRNA.
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