Residues 2-12 are the v-Src (412-422) autophosphorylation site with an extra Arg for phosphocellulose binding. This substrate sequence, RRLIEDNEYTARG, was originally described as an EGFR substrate in A431 cell extracts (Km=0.3-0.6 mM).
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Regulatory Status |
RUO – Research Use Only |
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