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pp242 . hydrate

ENZ-CHM132

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Inhibitor of both mTORC1 and mTORC2. Induces cell death in human and murine leukemia cells.

Inhibitor of the active site of mTOR kinase in both mTORC1 and mTORC2. pp242 has been shown to cause the death of certain human and murine leukemia cells more potently than rapamycin.

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Product Details

Alternative Name	PP-242, 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol, 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
Appearance	White powder solid.
CAS	1092351-67-1
Couple Target	mTOR
Couple Type	Inhibitor
Formula	C₁₆H₁₆N₆O . H₂O
MW	326.3
Purity	≥99% (HPLC)
Solubility	Soluble in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Short Term Storage	-20°C
Long Term Storage	-80°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Last modified: May 29, 2024

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pp242 . hydrate

ENZ-CHM132

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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