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Poly(ADP-ribose) monoclonal antibody

BML-SA216

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Product Details

Alternative Name	PAR
Application	ELISA, ICC, IP, WB
Clone	10HA
Formulation	Liquid. In TBS containing glycerol.
Host	Mouse
Immunogen	Purified poly(ADP-ribose) polymer (chain length of 2-50 units).
Isotype	IgG3
Purity Detail	Purified from mouse ascites.
Recommendation Dilutions/Conditions	Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Species independent
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Phosphorylated Y14 condensates as a scaffold for DNA double-strand break repair: Su, C. H., Chuang, T. W., et al.; iScience 28, 113073 (2025), Abstract
Discovery of Novel 4-Hydroxyquinazoline Derivatives: In Silico, In Vivo and In Vitro Studies Using Primary PARPi-Resistant Cell Lines: L. Zhu, et al.; Molecules 29, 1407 (2024), Abstract
PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization: Jankó, L., Tóth, E., et al.; Sci. Rep. 13, 7869 (2023), Abstract
Anti-inflammatory α-Melanocyte-Stimulating Hormone Protects Retina After Ischemia/Reperfusion Injury in Type I Diabetes.: Taylor, A. W., Goit, R. K., et al.; Front. Neurosci. 16, 799739 (2022), Application(s): IHC / Reactant(s): Mouse, Abstract
First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells.: Fernández Villamil, S. H., Valsecchi, W. M., et al.; PeerJ 9, e11442 (2021), Application(s): ICC-IF, Abstract
PARP Inhibitor Olaparib Causes No Potentiation of the Bleomycin Effect in VERO Cells, Even in the Presence of Pooled ATM, DNA-PK, and LigIV Inhibitors.: Perini, V., Schacke, M., et al.; Int. J. Mol. Sci. 21, (2020), Reactant(s): Green monkey, Abstract
Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis.: Kiss, B., Szántó, M., et al.; Exp. Dermatol. 29, 79 (2020), Application(s): WB, Abstract
Silencing of PARP2 Blocks Autophagic Degradation: L. Janko, et al.; Cells 9, 380 (2020), Reactant(s) Mouse, Abstract — Full Text
PARP-1/2 Inhibitor Olaparib Prevents or Partially Reverts EMT Induced by TGF-β in NMuMG Cells: M. Schacke, et al.; Int. J. Mol. Sci. 20, 518 (2019), Application(s): ICC-IF / Reactant(s) Mouse, Abstract — Full Text
NAD+ consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival.: Murata, M. M., Kong, X., et al.; Mol. Biol. Cell 30, 2584 (2019), Application(s): IF, Abstract

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